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. 1975 Apr;74(2):289–299. doi: 10.1017/s0022172400024360

The problem and implications of chloramphenicol resistance in the typhoid bacillus.

E S Anderson
PMCID: PMC2130376  PMID: 1091698

Abstract

Transferable chloramphenicol resistance has become common in the typhoid bacillus in countries such as Mexico, India, Vietnam and Thailand. Situations such as this, and others analogous to it in many parts of the world, are the result of the long-term indiscriminate use of chloramphenicol and other antibiotics in the affected areas. They can be rectified only by more rational antibiotic usage.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AKIBA T., KOYAMA K., ISHIKI Y., KIMURA S., FUKUSHIMA T. On the mechanism of the development of multiple-drug-resistant clones of Shigella. Jpn J Microbiol. 1960 Apr;4:219–227. doi: 10.1111/j.1348-0421.1960.tb00170.x. [DOI] [PubMed] [Google Scholar]
  2. Anderson E. S. A rapid screening test for transfer factors in drug-sensitive Enterobacteriaceae. Nature. 1965 Dec 4;208(5014):1016–1017. doi: 10.1038/2081016a0. [DOI] [PubMed] [Google Scholar]
  3. Anderson E. S., Smith H. R. Chloramphenicol resistance in the typhoid bacillus. Br Med J. 1972 Aug 5;3(5822):329–331. doi: 10.1136/bmj.3.5822.329. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Anderson E. S., Threlfall E. J., Carr J. M., Savoy L. G. Bacteriophage restriction in Salmonella typhimurium by R factors and transfer factors. J Hyg (Lond) 1973 Sep;71(3):619–631. doi: 10.1017/s0022172400046611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Butler T., Linh N. N., Arnold K., Pollack M. Chloramphenicol-resistant typhoid fever in Vietnam associated with R factor. Lancet. 1973 Nov 3;302(7836):983–985. doi: 10.1016/s0140-6736(73)91086-6. [DOI] [PubMed] [Google Scholar]
  6. Chabbert Y. A., Gerbaud G. R. Surveillance épidémiologique des plasmides responsables de la résistance au chloramphénicol de Salmonella typhi. Ann Microbiol (Paris) 1974 Feb-Mar;125A(2):153–166. [PubMed] [Google Scholar]
  7. ERSLEV A. J. DRUG-INDUCED BLOOD DYSCRASIAS. I. APLASTIC ANEMIA. JAMA. 1964 May 11;188:531–532. doi: 10.1001/jama.1964.03060320053013. [DOI] [PubMed] [Google Scholar]
  8. Grindley N. D., Grindley J. N., Anderson E. S. R factor compatibility groups. Mol Gen Genet. 1972;119(4):287–297. doi: 10.1007/BF00272087. [DOI] [PubMed] [Google Scholar]
  9. Grindley N. D., Humphreys G. O., Anderson E. S. Molecular studies of R factor compatibility groups. J Bacteriol. 1973 Jul;115(1):387–398. doi: 10.1128/jb.115.1.387-398.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Lampe R. M., Mansuwan P., Duangmani C. Letter: Chloramphenicol--resistant typhoid. Lancet. 1974 Apr 6;1(7858):623–624. doi: 10.1016/s0140-6736(74)92678-6. [DOI] [PubMed] [Google Scholar]
  11. Meynell E., Datta N. The nature and incidence of conjugation factors in Escherichia coli. Genet Res. 1966 Feb;7(1):141–148. doi: 10.1017/s001667230000954x. [DOI] [PubMed] [Google Scholar]
  12. Meynell E., Datta N. The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12. Genet Res. 1966 Feb;7(1):134–140. doi: 10.1017/s0016672300009538. [DOI] [PubMed] [Google Scholar]
  13. Paniker C. K., Vimala K. N. Transferable chloramphenicol resistance in Salmonella typhi. Nature. 1972 Sep 8;239(5367):109–110. doi: 10.1038/239109b0. [DOI] [PubMed] [Google Scholar]
  14. Smith H. R., Grindley N. D., Humphreys G. O., Anderson E. S. Interactions of group H resistance factors with the F factor. J Bacteriol. 1973 Aug;115(2):623–628. doi: 10.1128/jb.115.2.623-628.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Smith H. R., Humphreys G. O., Anderson E. S. Genetic and molecular characterisation of some non-transferring plasmids. Mol Gen Genet. 1974 Mar 27;129(3):229–242. doi: 10.1007/BF00267915. [DOI] [PubMed] [Google Scholar]
  16. Waldvogel F. A., Pitton J. S. Typhoid fever imported from Mexico to Switzerland. Studies on R factor mediated chloramphenicol resistance. J Hyg (Lond) 1973 Sep;71(3):509–513. doi: 10.1017/s0022172400046490. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wallerstein R. O., Condit P. K., Kasper C. K., Brown J. W., Morrison F. R. Statewide study of chloramphenicol therapy and fatal aplastic anemia. JAMA. 1969 Jun 16;208(11):2045–2050. [PubMed] [Google Scholar]

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