Skip to main content
NCBI home page
The Journal of Hygiene logoLink to The Journal of Hygiene
. 1974 Jun;72(3):379–387. doi: 10.1017/s0022172400023615

Determination of the colonization resistance of the digestive tract of individual mice

D van der Waaij, J M Berghuis
PMCID: PMC2130522  PMID: 4602039

Abstract

It has been shown that it is possible to investigate the colonization resistance in individual mice by determining the concentration of a certain contaminant (S.R.-E. coli) in the faeces during the first 4 days after contamination. Experimental contamination is contra-indicated in many cases such as in individuals with decreased resistance to infection. Particularly in this group, the value of the colonization resistance should be determined. It appeared to be possible to determine the colonization resistance in such individuals by quantitative biotyping of the Enterobacteriaceae species in the faeces on several consecutive days.

Full text

PDF
379

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abrams G. D., Bishop J. E. Effect of the normal microbial flora on the resistance of the small intestine to infection. J Bacteriol. 1966 Dec;92(6):1604–1608. doi: 10.1128/jb.92.6.1604-1608.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bazin H., Maldague P., Heremans J. F. The metabolism of different immunoglobulin classes in irradiated mice. II. Role of the gut. Immunology. 1970 Mar;18(3):361–368. [PMC free article] [PubMed] [Google Scholar]
  3. Bazin H., Maldague P., Schonne E., Crabbé P. A., Bauldon H., Heremans J. F. The metabolism of different immunoglobulin classes in irradiated mice. V. Contribution of the gut to serum IgA levels in normal and irradiated mice. Immunology. 1971 Apr;20(4):571–595. [PMC free article] [PubMed] [Google Scholar]
  4. Dennison S., Hedges R. W. Host specificities of RNA phages. J Hyg (Lond) 1972 Mar;70(1):55–61. doi: 10.1017/s0022172400022099. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Freter R. Parameters affecting the association of vibrios with the intestinal surface in experimental cholera. Infect Immun. 1972 Aug;6(2):134–141. doi: 10.1128/iai.6.2.134-141.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. GORDON L. E., RUML D., HAHNE H. J., MILLER C. P. Studies on susceptibility to infection following ionizing radiation. IV. The pathogenesis of the endogenous bacteremias in mice. J Exp Med. 1955 Oct 1;102(4):413–424. doi: 10.1084/jem.102.4.413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Williams R. C., Gibbons R. J. Inhibition of bacterial adherence by secretory immunoglobulin A: a mechanism of antigen disposal. Science. 1972 Aug 25;177(4050):697–699. doi: 10.1126/science.177.4050.697. [DOI] [PubMed] [Google Scholar]
  8. van der Waaij D., Andreas A. H. Prevention of airborne contamination and cross-contamination in germ-free mice by laminar flow. J Hyg (Lond) 1971 Mar;69(1):83–89. doi: 10.1017/s0022172400021276. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. van der Waaij D., Berghuis-de Vries J. M., Lekkerkerk Lekkerkerk-v Colonization resistance of the digestive tract in conventional and antibiotic-treated mice. J Hyg (Lond) 1971 Sep;69(3):405–411. doi: 10.1017/s0022172400021653. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. van der Waaij D., Speltie T. M., Vossen J. M. Biotyping of Enterobacteriaceae as a test for the evaluation of isolation systems. J Hyg (Lond) 1972 Dec;70(4):639–650. doi: 10.1017/s0022172400022506. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Hygiene are provided here courtesy of Cambridge University Press

RESOURCES