Abstract
The effects of oral chemotherapy and stay in hospital on the antibiotic resistance patterns of faecal coliform flora were studied. The coliform flora of 64% of 25 patients who were not receiving antibiotics was sensitive to all drugs tested. Hospitalization alone did not affect this proportion. The administration of tetracycline or ampicillin to patients, whether at home or in hospital, significantly increased the percentage of resistant bowel coliforms. Tetracycline showed a significantly greater effect than ampicillin. There was no significant increase in the percentage of patients with resistant flora after treatment with amoxycillin.
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- Datta N. Drug resistance and R factors in the bowel bacteria of London patients before and after admission to hospital. Br Med J. 1969 May 17;2(5654):407–411. doi: 10.1136/bmj.2.5654.407. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Datta N., Faiers M. C., Reeves D. S., Brumfitt W., Orskov F., Orskov I. R Factors in Escherichia coli in faeces after oral chemotherapy in general practice. Lancet. 1971 Feb 13;1(7694):312–315. doi: 10.1016/s0140-6736(71)91042-7. [DOI] [PubMed] [Google Scholar]
- Moorhouse E. C. Transferable drug resistance in enterobacteria isolated from urban infants. Br Med J. 1969 May 17;2(5654):405–407. doi: 10.1136/bmj.2.5654.405. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sutherland R., Croydon E. A., Rolinson G. N. Amoxycillin: a new semi-synthetic penicillin. Br Med J. 1972 Jul 1;3(5817):13–16. doi: 10.1136/bmj.3.5817.13. [DOI] [PMC free article] [PubMed] [Google Scholar]