Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1925 Jul 31;42(2):253–274. doi: 10.1084/jem.42.2.253

STUDIES ON THE ETIOLOGY OF HEARTWATER

II. RICKETTSIA RUMINANTIUM (N. SP.) IN THE TISSUES OF TICKS TRANSMITTING THE DISEASE.

E V Cowdry 1
PMCID: PMC2130996  PMID: 19869050

Abstract

The evidence offered in the first of these studies indicative of a causative relationship between Rickettsia ruminantium and heartwater is supplemented by the following observations concerning the ticks which carry the disease. When larvæ, which had taken no food since hatching, were allowed to feed upon cases of heartwater, they acquired Rickettsiœ which appeared to be identical with those in the tissues of animals suffering from heartwater, whereas control larvæ hatched from eggs deposited by the same female and fed on normal animals remained free of Rickettsiœ. After larvæ presumably infective had moulted, the resultant nymphæ containing Rickettsiœ in their alimentary tracts, when fed upon susceptible animals produced in them typical attacks of heartwater, which the control nymphae, devoid of Rickettsiœ, failed to do. The tissues of animals thus infected were found upon histological examination to contain typical Rickettsioelig;.

Full Text

The Full Text of this article is available as a PDF (1.2 MB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cowdry E. V. THE DISTRIBUTION OF RICKETTSIA IN THE TISSUES OF INSECTS AND ARACHNIDS. J Exp Med. 1923 Mar 31;37(4):431–456. doi: 10.1084/jem.37.4.431. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Wolbach S. B., Schlesinger M. J. The Cultivation of the Micro-Organisms of Rocky Mountain spotted Fever (Dermacentroxenus Rickettsi) and of Typhus (Rickettsia Prowazeki) in Tissue Cultures. J Med Res. 1923 Dec;44(2):231–256.1. doi: 10.3181/00379727-20-129. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES