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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1926 Feb 28;43(3):395–402. doi: 10.1084/jem.43.3.395

COMPENSATORY HYPERTROPHY OF THE ADRENAL CORTEX

Eaton M MacKay 1, Lois Lockard MacKay 1
PMCID: PMC2131105  PMID: 19869131

Abstract

1. Removal of one adrenal in the albino rat is followed by hypertrophy of the remaining gland. In the case of female rats 90 days of age this compensatory hypertrophy amounted to 61 per cent. 2. The increase in size of the whole gland is due entirely to hypertrophy of the cortex. This increase in cortical tissue amounted to approximately 91 per cent and was due in large part if not entirely to an increase in the size of the cells. 3. No increase in the size of the medulla or its cells was found.

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Selected References

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  1. Elliott T. R., Tuckett I. Cortex and medulla in the suprarenal glands. J Physiol. 1906 Aug 10;34(4-5):332–390.1. doi: 10.1113/jphysiol.1906.sp001161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Scott W. J. THE INFLUENCE OF THE ADRENAL GLANDS ON RESISTANCE : I. THE SUSCEPTIBILITY OF ADRENALECTOMIZED RATS TO MORPHINE. J Exp Med. 1923 Oct 31;38(5):543–560. doi: 10.1084/jem.38.5.543. [DOI] [PMC free article] [PubMed] [Google Scholar]

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