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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1927 Aug 31;46(3):497–509. doi: 10.1084/jem.46.3.497

STUDIES ON STREPTOCOCCUS BACTERIOPHAGE

I. A POWERFUL LYTIC PRINCIPLE AGAINST HEMOLYTIC STREPTOCOCCI OF ERYSIPELAS ORIGIN.

Gregory Shwartzman 1
PMCID: PMC2131241  PMID: 19869351

Abstract

1. The "sludge" phage obtained by Clark and Clark answers all requirements for pronouncing it identical with the classical bacteriophage. 2. The "sludge" phage failed to produce lysis in any of the 102 human pathogenic streptococci tested. 3. Numerous attempts to induce regeneration of various lytic principles by human streptococci resulted in failure. 4. It was possible, however, to "train" erysipelas streptococci to regenerate a lytic principle active against 76 per cent of strains of this group. 5. The erysipelas phage showed remarkable specificity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Shwartzman G. STUDIES ON REGENERATION OF BACTERIOPHAGE : I. THE INFLUENCE OF PARTIAL ANAEROBIOSIS UPON REGENERATION OF A HIGHLY DILUTED LYTIC PRINCIPLE. J Exp Med. 1925 Sep 30;42(4):507–516. doi: 10.1084/jem.42.4.507. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Shwartzman G. STUDIES ON REGENERATION OF BACTERIOPHAGE : II. THE INFLUENCE OF OXYGEN UPON THE BEHAVIOR OF BACILLUS COLI TOWARDS LYTIC PRINCIPLE. J Exp Med. 1926 May 31;43(6):743–751. doi: 10.1084/jem.43.6.743. [DOI] [PMC free article] [PubMed] [Google Scholar]

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