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. 1928 Jan 1;47(1):171–181. doi: 10.1084/jem.47.1.171

ON PRECIPITABLE SUBSTANCES DERIVED FROM BACILLUS TYPHOSUS AND BACILLUS PARATYPHOSUS B

J Furth 1, K Landsteiner 1
PMCID: PMC2131348  PMID: 19869396

Abstract

Attempts to confirm certain statements that ether-soluble specific substances can be obtained from B. typhosus have lead to negative results. Two serologically active protein substances and another that was non-protein have been separated from B. typhosus. The first two are not resistant to tryptic digestion or to treatment with alkaline hypochlorite solution whereas the third resists both. One of the proteins could be extracted with 75 per cent alcohol. Specific precipitable substances reacting like the non-protein substance of B. typhosus and containing large amounts of carbohydrates have been prepared from B. paratyphosus B, B. enteritidis, and Proteus HX19 and OX19. Observations on the serological behaviour of these preparations are described.

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Selected References

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  1. Avery O. T., Morgan H. J. IMMUNOLOGICAL REACTIONS OF THE ISOLATED CARBOHYDRATE AND PROTEIN OF PNEUMOCOCCUS. J Exp Med. 1925 Aug 31;42(3):347–353. doi: 10.1084/jem.42.3.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Beyer H. G., Reagh A. L. The further Differentiation of Flagellar and Somatic Agglutinins. J Med Res. 1904 Oct;12(3):313–328. [PMC free article] [PubMed] [Google Scholar]
  3. Landsteiner K., Levine P. ON A SPECIFIC SUBSTANCE OF THE CHOLERA VIBRIO. J Exp Med. 1927 Jul 31;46(2):213–221. doi: 10.1084/jem.46.2.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Landsteiner K., van der Scheer J. ON THE ANTIGENS OF RED BLOOD CORPUSCLES : II. FLOCCULATION REACTIONS WITH ALCOHOLIC EXTRACTS OF ERYTHROCYTES. J Exp Med. 1925 Jul 31;42(2):123–142. doi: 10.1084/jem.42.2.123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Orcutt M. L. THE EFFECT OF HEAT ON FLAGELLAR AND SOMATIC AGGLUTINATION. J Exp Med. 1924 Oct 31;40(5):627–632. doi: 10.1084/jem.40.5.627. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Smith T., Reagh A. L. The Non-Identity of Agglutinins Acting upon the Flagella and upon the Body of Bacteria. J Med Res. 1903 Aug;10(1):89–100. [PMC free article] [PubMed] [Google Scholar]
  7. Zinsser H., Parker J. T. FURTHER STUDIES ON BACTERIAL HYPERSUSCEPTIBILITY. II. J Exp Med. 1923 Jan 31;37(2):275–302. doi: 10.1084/jem.37.2.275. [DOI] [PMC free article] [PubMed] [Google Scholar]

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