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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1929 Apr 30;49(5):759–764. doi: 10.1084/jem.49.5.759

TOTAL SURGICAL REMOVAL OF THE LIVER IN RABBITS

D R Drury 1
PMCID: PMC2131581  PMID: 19869580

Abstract

A technique is described for total removal of the liver of the rabbit without circulatory difficulties as a result. The method requires a preliminary operation to induce a development of portal and caval collaterals. Rabbits deprived of the liver in this manner if given glucose live for varying periods up to 40 hours. Before death they show the same disturbances as do hepatectomized dogs. They die early, of hypoglycemia, unless provided with sugar.

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Selected References

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  1. McMaster P. D., Drury D. R. THE PRODUCTION OF PARTIAL LIVER INSUFFICIENCY IN RABBITS. J Exp Med. 1929 Apr 30;49(5):745–758. doi: 10.1084/jem.49.5.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
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