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. 1929 Nov 30;50(6):809–823. doi: 10.1084/jem.50.6.809

A QUANTITATIVE STUDY OF THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND PURIFIED HOMOLOGOUS ANTIBODY

Michael Heidelberger 1, Forrest E Kendall 1
PMCID: PMC2131658  PMID: 19869667

Abstract

1. A quantitative study of the reaction between the soluble specific substance of Type III pneumococcus and its homologous antibody has been made. 2. The entire reaction, from excess of antibody, to excess of specific substance with its accompanying inhibition zone effect, may be expressed by three mass-law equations. 3. The significance of these findings is discussed.

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Selected References

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  1. Heidelberger M., Goebel W. F., Avery O. T. THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER. J Exp Med. 1925 Oct 31;42(5):727–745. doi: 10.1084/jem.42.5.727. [DOI] [PMC free article] [PubMed] [Google Scholar]

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