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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1930 Jan 31;51(2):189–207. doi: 10.1084/jem.51.2.189

ON THE RELATION OF THE ORGANISMS IN THE TUNICA VAGINALIS OF ANIMALS INOCULATED WITH MEXICAN TYPHUS TO RICKETTSIA PROWAZEKI AND TO THE CAUSATIVE AGENT OF THAT DISEASE

H Mooser 1, Clyde Dummer 1
PMCID: PMC2131814  PMID: 19869683

Abstract

Healthy lice became infected with Rickettsia prowazeki after feeding on monkeys inoculated with a strain of Mexican typhus. The same result was obtained in 100 per cent of lice by rectal inoculation of an emulsion of tunica vaginalis of guinea pigs reacting to the same strain. In the tunica vaginalis of guinea pigs and rats inoculated intraperitoneally with an emulsion of lice containing Rickettsia prowazeki the intracellular organism constantly associated with the passage strain appeared regularly. Rickettsia prowazeki found in lice and the organism constantly present in the tunica of guinea pigs and rats reacting to our strain of tabardillo are indistinguishable morphologically and tinctorially and their mode of intracellular multiplication is alike in every respect. It is concluded that they are identical. This organism is constantly associated with the causative agent of Mexican typhus, both in mammals and in lice, and all of our attempts to separate them have failed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Olitsky P. K. EXPERIMENTAL STUDIES ON THE ETIOLOGY OF TYPHUS FEVER : III. FILTRATION EXPERIMENTS. J Exp Med. 1922 Jan 31;35(2):121–126. doi: 10.1084/jem.35.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Public Health Weekly Reports for AUGUST 9, 1929. Public Health Rep. 1929 Aug 9;44(32):1935–1994. [PMC free article] [PubMed] [Google Scholar]
  3. Public Health Weekly Reports for MAY 31, 1912. Public Health Rep. 1912 May 31;27(22):835–894. [PMC free article] [PubMed] [Google Scholar]

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