Abstract
1. The upper respiratory tract is sterile at birth. 2. In the first 2 weeks of life the infant acquires a basal flora comparable to that of adults except that the potential pathogens are absent. 3. During the ensuing months the potential pathogens may appear without giving rise to symptoms and by 8 months the infant's flora is entirely comparable to the adult's. 4. There is no evidence of a specific bacterial incitant for the first colds of infancy. 5. In infants with recurrent colds, secondary infection of the nose with pneumococci or B. pfeifferi probably plays a part.
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Selected References
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- Burky E. L., Smillie W. G. NASOPHARYNGEAL FLORA IN HEALTH AND DURING RESPIRATORY DISEASE IN ISOLATED COMMUNITIES IN ALABAMA AND LABRADOR. J Exp Med. 1929 Oct 31;50(5):643–663. doi: 10.1084/jem.50.5.643. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Olitsky P. K., Gates F. L. EXPERIMENTAL STUDIES OF THE NASOPHARYNGEAL SECRETIONS FROM INFLUENZA PATIENTS : IX. THE RECURRENCE OF 1922. J Exp Med. 1922 Oct 31;36(5):501–519. doi: 10.1084/jem.36.5.501. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shibley G. S., Hanger F. M., Dochez A. R., Assistance of Katherine C. Mills STUDIES IN THE COMMON COLD : I. OBSERVATIONS OF THE NORMAL BACTERIAL FLORA OF NOSE AND THROAT WITH VARIATIONS OCCURRING DURING COLDS. J Exp Med. 1926 Feb 28;43(3):415–431. doi: 10.1084/jem.43.3.415. [DOI] [PMC free article] [PubMed] [Google Scholar]