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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1930 Mar 31;51(4):519–529. doi: 10.1084/jem.51.4.519

THE IMMUNOLOGICAL SIGNIFICANCE OF COLOSTRUM

III. INTRANUCLEAR BODIES IN RENAL DISEASE OF CALVES

Theobald Smith 1
PMCID: PMC2131845  PMID: 19869708

Abstract

Renal lesions chiefly the result of obstructive processes were associated with intranuclear bodies in the epithelium of straight and convoluted tubules. In one animal these bodies were found in large numbers in otherwise still normal organs. The affected animals had been fed cow serum in place of colostrum.

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Selected References

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  1. Smith T. FOCAL INTERSTITIAL NEPHRITIS IN THE CALF FOLLOWING INTERFERENCE WITH THE NORMAL INTAKE OF COLOSTRUM. J Exp Med. 1925 Feb 28;41(3):413–425. doi: 10.1084/jem.41.3.413. [DOI] [PMC free article] [PubMed] [Google Scholar]

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