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. 1930 Aug 31;52(3):379–384. doi: 10.1084/jem.52.3.379

A METHOD FOR SUPRAVITAL STAINING OF ANIMALS WITH NEUTRAL RED AND ITS PRESERVATION IN PARAFFIN SECTIONS

Claude E Forkner 1
PMCID: PMC2131880  PMID: 19869771

Abstract

A simple, rapid method for staining all the supravitally stainable cells in the body, as in supravital preparations with neutral red, is described, together with a method for faithful preservation of the dye in paraffin sections. The essential points of the technique are, first, to secure the reaction of cells to neutral red which corresponds to the so-called supravital technique, involving the reaction of only those substances which respond to the dye while the cell is living; and second, to preserve the stain through the processes of fixation, embedding, and counterstaining.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Forkner C. E. MATERIAL FROM LYMPH NODES : IV. THE HETEROLOGY OF LYMPHOID TISSUE WITH SPECIAL REFERENCE TO THE MONOCYTE-SUPRAVITAL STUDIES. J Exp Med. 1929 Jan 31;49(2):323–345. doi: 10.1084/jem.49.2.323. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Forkner C. E. THE ORIGIN AND FATE OF TWO TYPES OF MULTI-NUCLEATED GIANT CELLS IN THE CIRCULATING BLOOD. J Exp Med. 1930 Jul 31;52(2):279–297. doi: 10.1084/jem.52.2.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Forkner C. E. THE ORIGIN OF MONOCYTES IN CERTAIN LYMPH NODES AND THEIR GENETIC RELATION TO OTHER CONNECTIVE TISSUE CELLS. J Exp Med. 1930 Aug 31;52(3):385–404. doi: 10.1084/jem.52.3.385. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. McJunkin F. A. The Origin of the Mononuclear Phagocytes of Peritoneal Exudates. Am J Pathol. 1925 May;1(3):305–324. [PMC free article] [PubMed] [Google Scholar]

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