Abstract
A steeply mounting gradient of permeability is demonstrable along the meshwork of capillaries which connects the arterioles and venules of the skin of the frog. The venules incorporated in the meshwork are even more permeable than the capillary meshes giving into them. The presence of the gradient under such differing conditions as exist along frog and mammalian capillaries enables one to rule out certain factors which might be invoked to explain it; and it is not explainable in terms of those influences generally recognized as conditioning exchange between the blood and tissues. Not improbably it results from a structural differentiation along the capillary.
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Selected References
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- Churchill E. D., Nakazawa F., Drinker C. K. The circulation of body fluids in the frog. J Physiol. 1927 Aug 8;63(3):304–308. doi: 10.1113/jphysiol.1927.sp002405. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Krogh A. Studies on the physiology of capillaries: II. The reactions to local stimuli of the blood-vessels in the skin and web of the frog. J Physiol. 1921 Nov 18;55(5-6):412–422. doi: 10.1113/jphysiol.1921.sp001985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rous P., Gilding H. P., Smith F. THE GRADIENT OF VASCULAR PERMEABILITY. J Exp Med. 1930 Apr 30;51(5):807–830. doi: 10.1084/jem.51.5.807. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith F., Rous P. THE GRADIENT OF VASCULAR PERMEABILITY : II. THE CONDITIONS IN FROG AND CHICKEN MUSCLE, AND IN THE MAMMALIAN DIAPHRAGM. J Exp Med. 1931 Jan 31;53(2):195–217. doi: 10.1084/jem.53.2.195. [DOI] [PMC free article] [PubMed] [Google Scholar]