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. 1931 Jul 31;54(3):431–436. doi: 10.1084/jem.54.3.431

CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS

IV. THE SYNTHESIS OF THEp-AMINOBENZYL ETHER OF THE SOLUBLE SPECIFIC SUBSTANCE OF TYPE III PNEUMOCOCCUS AND ITS COUPLING WITH PROTEIN

Walther F Goebel 1, Oswald T Avery 1
PMCID: PMC2132012  PMID: 19869929

Abstract

1. The p-amino and p-nitromonobenzyl ethers of the specific polysaccharide of Type III Pneumococcus have been prepared. 2. The diazonium ether of the specific polysaccharide has been coupled with serum globulin to yield a specific polysaccharide-protein complex and this complex has been used for immunization. The results of the immunological studies are presented in the following paper.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Goebel W. F., Avery O. T. CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : I. THE SYNTHESIS OFp-AMINOPHENOL beta-GLUCOSIDE, p-AMINOPHENOL beta-GALACTOSIDE, AND THEIR COUPLING WITH SERUM GLOBULIN. J Exp Med. 1929 Sep 30;50(4):521–531. doi: 10.1084/jem.50.4.521. [DOI] [PMC free article] [PubMed] [Google Scholar]
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