Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1932 Jan 31;55(2):169–179. doi: 10.1084/jem.55.2.169

IMMUNOLOGICAL REACTIONS OF PNEUMONIC PLEURAL FLUIDS

Maxwell Finland 1
PMCID: PMC2132089  PMID: 19869983

Abstract

Pleuritic exudates from patients with lobar pneumonia may be sterile or infected. Sterile fluids, at or about the time of crisis, contain actively acquired antibodies similar to those in the blood serum. Infected fluids do not contain such antibodies, presumably because of the presence in them of large amounts of soluble specific substance. Sterile fluids from patients treated with immune sera have both horse serum and antibodies similar to those injected. Infected fluids from serum-treated cases contain horse serum and such heterologous antibodies as were contained in the therapeutic sera together with homologous soluble specific substance. The concentration of horse serum and antibodies in pneumonic fluids is usually the same or somewhat less than that of the corresponding blood sera.

Full Text

The Full Text of this article is available as a PDF (528.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amoss H. L., Eberson F. THE PASSAGE OF MENINGOCOCCIC AGGLUTININS FROM THE BLOOD TO THE SPINAL FLUID OF THE MONKEY. J Exp Med. 1919 Jun 1;29(6):597–603. doi: 10.1084/jem.29.6.597. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cole R. THE NEUTRALIZATION OF ANTIPNEUMOCOCCUS IMMUNE BODIES BY INFECTED EXUDATES AND SERA. J Exp Med. 1917 Oct 1;26(4):453–475. doi: 10.1084/jem.26.4.453. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dochez A. R. THE PRESENCE OF PROTECTIVE SUBSTANCES IN HUMAN SERUM DURING LOBAR PNEUMONIA. J Exp Med. 1912 Nov 1;16(5):665–679. doi: 10.1084/jem.16.5.665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Flexner S., Clark P. F., Amoss H. L. A CONTRIBUTION TO THE PATHOLOGY OF EPIDEMIC POLIOMYELITIS. J Exp Med. 1914 Feb 1;19(2):205–211. doi: 10.1084/jem.19.2.205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Freund J. ACCUMULATION OF ANTIBODIES IN THE CENTRAL NERVOUS SYSTEM. J Exp Med. 1930 May 31;51(6):889–902. doi: 10.1084/jem.51.6.889. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Menkin V., Menkin M. F. STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA. J Exp Med. 1930 Jan 31;51(2):285–293. doi: 10.1084/jem.51.2.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Menkin V. STUDIES ON INFLAMMATION : IV. FIXATION OF FOREIGN PROTEIN AT SITE OF INFLAMMATION. J Exp Med. 1930 Jul 31;52(2):201–213. doi: 10.1084/jem.52.2.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Tillett W. S., Francis T. CUTANEOUS REACTIONS TO THE POLYSACCHARIDES AND PROTEINS OF PNEUMOCOCCUS IN LOBAR PNEUMONIA. J Exp Med. 1929 Oct 31;50(5):687–701. doi: 10.1084/jem.50.5.687. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES