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. 1932 Apr 30;55(5):761–767. doi: 10.1084/jem.55.5.761

CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS

VI. THE SYNTHESIS OFp-AMINOPHENOLα-GLUCOSIDE AND ITS COUPLING WITH PROTEIN

Walther F Goebel 1, Frank H Babers 1, Oswald T Avery 1
PMCID: PMC2132141  PMID: 19870028

Abstract

1. The synthesis of p-aminophenol α-glucoside has been described. This glucoside can be coupled to any protein to yield a synthetic α-glucoside-protein complex. 2. A synthetic β-glucoside-protein complex has also been prepared. 3. These synthetic sugar-protein complexes have been used as immunizing antigens in order to ascertain whether α- and β-glucosidic unions influence the specificity of the immune response in animals. The results of the immunological studies are presented in the following paper.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Avery O. T., Goebel W. F. CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : II. IMMUNOLOGICAL SPECIFICITY OF SYNTHETIC SUGAR-PROTEIN ANTIGENS. J Exp Med. 1929 Sep 30;50(4):533–550. doi: 10.1084/jem.50.4.533. [DOI] [PMC free article] [PubMed] [Google Scholar]
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