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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1933 Mar 31;57(4):561–569. doi: 10.1084/jem.57.4.561

STUDIES ON MENINGOCOCCUS INFECTION

II. MONOVALENT DIAGNOSTIC SERA PREPARED FROM "FRESH" AND "STOCK" STRAINS

Geoffrey Rake 1
PMCID: PMC2132243  PMID: 19870147

Abstract

The production of monovalent sera for agglutinin or precipitin reactions with freshly isolated strains of meningococci is described. Agglutination reactions with such sera can be carried out more rapidly, at lower temperatures and in lower dilutions, than with the standard monovalent sera prepared from stock cultures, while the results so obtained are more satisfactory owing to the relative absence of cross-agglutination.

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