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. 1933 Jul 31;58(2):153–160. doi: 10.1084/jem.58.2.153

THE EFFECT OF PNEUMOCOCCUS AUTOLYSATES UPON PNEUMOCOCCUS DERMAL INFECTION IN THE RABBIT

Kenneth Goodner 1
PMCID: PMC2132291  PMID: 19870186

Abstract

In pneumococcus dermal infections in rabbits, the addition of pneumococcus autolysate to an infective inoculum favors the invasiveness of the particular strain employed, but does not alter the kind of virulence possessed by that strain. Autolysates exhibiting this enhancing property also induce purpura in mice and inhibit the coagulation of rabbit blood. The relation of these properties to the infectivity of Pneumococcus and the possible role of bacterial autolysis in natural infection are discussed.

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Selected References

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  1. Goodner K. FURTHER EXPERIMENTS WITH THE INTRADERMAL PNEUMOCOCCUS INFECTION IN RABBITS. J Exp Med. 1928 Aug 31;48(3):413–429. doi: 10.1084/jem.48.3.413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Goodner K. THE DEVELOPMENT AND LOCALIZATION OF THE DERMAL PNEUMOCOCCIC LESION IN THE RABBIT. J Exp Med. 1931 Nov 30;54(6):847–858. doi: 10.1084/jem.54.6.847. [DOI] [PMC free article] [PubMed] [Google Scholar]

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