Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1990 Aug;172(8):4725–4727. doi: 10.1128/jb.172.8.4725-4727.1990

A cyanide-aldehyde complex inhibits bacterial luciferase.

J C Makemson 1
PMCID: PMC213315  PMID: 2376571

Abstract

Cyanide at high (millimolar) concentrations inhibited in the in vitro Vibrio harveyi luciferase reaction. Cyanide reacted with free aldehyde to form an inhibitor. Inhibitor formation was accelerated by alkaline conditions and bovine serum albumin.

Full text

PDF
4725

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baldwin T. O., Holzman T. F., Holzman R. B., Riddle V. A. Purification of bacterial luciferase by affinity methods. Methods Enzymol. 1986;133:98–108. doi: 10.1016/0076-6879(86)33058-1. [DOI] [PubMed] [Google Scholar]
  2. Baumstark A. L., Cline T. W., Hastings J. W. Reversible steps in the reaction of aldehydes with bacterial luciferase intermediates. Arch Biochem Biophys. 1979 Apr 1;193(2):449–455. doi: 10.1016/0003-9861(79)90051-1. [DOI] [PubMed] [Google Scholar]
  3. Hastings J. W., Potrikus C. J., Gupta S. C., Kurfürst M., Makemson J. C. Biochemistry and physiology of bioluminescent bacteria. Adv Microb Physiol. 1985;26:235–291. doi: 10.1016/s0065-2911(08)60398-7. [DOI] [PubMed] [Google Scholar]
  4. Makemson J. C. Luciferase-dependent oxygen consumption by bioluminescent vibrios. J Bacteriol. 1986 Feb;165(2):461–466. doi: 10.1128/jb.165.2.461-466.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Makemson J., Hastings J. W. Inhibition of bacterial bioluminescence by pargyline. Arch Biochem Biophys. 1979 Sep;196(2):396–402. doi: 10.1016/0003-9861(79)90290-x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES