Abstract
1. The effect of various percentages of protein (casein) in the diet on the serum protein concentration of the rat was studied. 2. With high protein rations (50 per cent or over) there is no drop at all of serum protein concentration, even though the diet is otherwise poorly balanced and inadequate as evidenced by weight loss. 3. With protein rations under 20 per cent the serum protein concentration falls promptly to a level of about 5.25–5.50 gm. per cent, where it is maintained regardless of whether the diet contains 1, 5, or 10 per cent of protein. Further depletion of the blood colloid concentration seems to meet with resistance on the part of the body.
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Selected References
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- Barnett C. W., Jones R. B., Cohn R. B. THE MAINTENANCE OF A NORMAL PLASMA PROTEIN CONCENTRATION IN SPITE OF REPEATED PROTEIN LOSS BY BLEEDING. J Exp Med. 1932 Apr 30;55(5):683–693. doi: 10.1084/jem.55.5.683. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bloomfield A. L. THE EFFECT OF CARROT FEEDING ON THE SERUM PROTEIN CONCENTRATION OF THE RAT. J Exp Med. 1934 May 31;59(6):687–698. doi: 10.1084/jem.59.6.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bloomfield A. L. THE EFFECT OF RESTRICTION OF PROTEIN INTAKE ON THE SERUM PROTEIN CONCENTRATION OF THE RAT. J Exp Med. 1933 Apr 30;57(5):705–720. doi: 10.1084/jem.57.5.705. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Holman R. L., Mahoney E. B., Whipple G. H. BLOOD PLASMA PROTEIN GIVEN BY VEIN UTILIZED IN BODY METABOLISM : II. A DYNAMIC EQUILIBRIUM BETWEEN PLASMA AND TISSUE PROTEINS. J Exp Med. 1934 Feb 28;59(3):269–282. doi: 10.1084/jem.59.3.269. [DOI] [PMC free article] [PubMed] [Google Scholar]