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. 1935 Apr 30;61(5):689–702. doi: 10.1084/jem.61.5.689

ENCEPHALOMYELITIS ACCOMPANIED BY MYELIN DESTRUCTION EXPERIMENTALLY PRODUCED IN MONKEYS

Thomas M Rivers 1, Francis F Schwentker 1
PMCID: PMC2133246  PMID: 19870385

Abstract

The repeated intramuscular injections of aqueous emulsions and alcohol-ether extracts of sterile normal rabbit brains in some manner produced pathological changes accompanied by myelin destruction in the brains of 7 of 8 monkeys (Macacus rhesus). Eight, control monkeys remained well. Cultures from the involved brains remained sterile, and no transmissible agent was demonstrated by means of intracerebral inoculations of emulsions of bits of the brains into monkeys, rabbits, guinea pigs, and white mice.

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Selected References

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  1. Schwentker F. F., Rivers T. M. THE ANTIBODY RESPONSE OF RABBITS TO INJECTIONS OF EMULSIONS AND EXTRACTS OF HOMOLOGOUS BRAIN. J Exp Med. 1934 Oct 31;60(5):559–574. doi: 10.1084/jem.60.5.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
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