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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1935 Jul 31;62(2):245–257. doi: 10.1084/jem.62.2.245

ISOLATION OF POLIOMYELITIS VIRUS FROM THE NASOPHARYNX

John R Paul 1, James D Trask 1, Leslie T Webster 1
PMCID: PMC2133270  PMID: 19870412

Abstract

A single example of mild illness diagnosed as suspected abortive poliomyelitis is described in which the virus of poliomyelitis was recovered from the nasopharynx by three different methods. Failure to recover virus from a total of twenty-six cases diagnosed as suspected or abortive poliomyelitis and fourteen contacts is also reported. The original material from the nasopharynx of the positive case proved unusually infective for the monkey, apparently even more so than are the majority of suspensions of spinal cords from fatal human cases of poliomyelitis. An explanation of this fact is not clear. The method of isolating human virus from the throat, by means of preserving the sediment of washings from this site in glycerine, has been shown to be efficient in one case for a period of 101 days.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Kessel J. F., Hoyt A. S., Fisk R. T. Use of Serum and the Routine and Experimental Laboratory Findings in the 1934 Poliomyelitis Epidemic. Am J Public Health Nations Health. 1934 Dec;24(12):1215–1223. doi: 10.2105/ajph.24.12.1215. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Paul J. R., Trask J. D. THE DETECTION OF POLIOMYELITIS VIRUS IN SO CALLED ABORTIVE TYPES OF THE DISEASE. J Exp Med. 1932 Aug 31;56(3):319–343. doi: 10.1084/jem.56.3.319. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Taylor E., Amoss H. L. CARRIAGE OF THE VIRUS OF POLIOMYELITIS, WITH SUBSEQUENT DEVELOPMENT OF THE INFECTION. J Exp Med. 1917 Nov 1;26(5):745–754. doi: 10.1084/jem.26.5.745. [DOI] [PMC free article] [PubMed] [Google Scholar]

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