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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1935 Sep 30;62(4):517–521. doi: 10.1084/jem.62.4.517

INACTIVATION OF POLIOMYELITIS VIRUS IN VITRO BY CRYSTALLINE VITAMIN C (ASCORBIC ACID)

Claus W Jungeblut 1
PMCID: PMC2133291  PMID: 19870431

Abstract

The experimental evidence presented in this paper shows that multiple paralytic doses of poliomyelitis virus, when mixed with very small amounts of crystalline vitamin C (ascorbic acid), are rendered non-infectious as determined by intracerebral injection of such mixtures into rhesus monkeys.

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