Abstract
1. A protection test for measuring serological protective properties against the encephalitis (St. Louis type) virus is described. 2. Normal non-contact sera and sera from persons supposed to have had no exposure to the disease do not protect against the virus. 82.5 per cent of sera from tested St. Louis encephalitis convalescents and at least 66 per cent of sera from tested persons thought to have had the disease do show protective properties. 3. The protective activity of sera is maintained for at least 2½ years after onset of the disease. In vitro aging of serum decreases its activity. 4. Protection tests indicate that the virus was present as early as 1932 in Paris, Illinois, spread through the north central states and reached New York in 1933, and was again active in the north central states in 1934.
Full Text
The Full Text of this article is available as a PDF (1.0 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Rivers T. M., Schwentker F. F. LOUPING ILL IN MAN. J Exp Med. 1934 Apr 30;59(5):669–685. doi: 10.1084/jem.59.5.669. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Webster L. T., Fite G. L. A VIRUS ENCOUNTERED IN THE STUDY OF MATERIAL FROM CASES OF ENCEPHALITIS N THE ST. LOUIS AND KANSAS CITY EPIDEMICS OF 1933. Science. 1933 Nov 17;78(2029):463–465. doi: 10.1126/science.78.2029.463. [DOI] [PubMed] [Google Scholar]
- Webster L. T., Fite G. L. EXPERIMENTAL STUDIES ON ENCEPHALITIS : I. TRANSMISSION OF ST. LOUIS AND KANSAS CITY ENCEPHALITIS TO MICE. J Exp Med. 1935 Jan 1;61(1):103–114. doi: 10.1084/jem.61.1.103. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Webster L. T., Fite G. L. EXPERIMENTAL STUDIES ON ENCEPHALITIS : II. THE SPECIFIC VIRUS CHARACTER OF THE INFECTIOUS AGENT FROM CASES OF ST. LOUIS AND KANSAS CITY ENCEPHALITIS, 1933. J Exp Med. 1935 Feb 28;61(3):411–422. doi: 10.1084/jem.61.3.411. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Webster L. T., Fite G. L. ST. LOUIS ENCEPHALITIS. Science. 1934 Mar 16;79(2046):254–255. doi: 10.1126/science.79.2046.254. [DOI] [PubMed] [Google Scholar]