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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1937 Feb 28;65(3):339–345. doi: 10.1084/jem.65.3.339

ANAPHYLACTIC SENSITIZATION WITH CHEMICALLY DEFINITE COMPOUNDS

H E Fierz 1, W Jadassohn 1, W Stoll 1
PMCID: PMC2133493  PMID: 19870605

Abstract

Injection of sodium atoxyl-diazoamino-sulfoanthranilate into guinea pigs produces an anaphylactic hypersensitiveness to the corresponding azoprotein (Schultz-Dale test). This leads to the conclusion that the injected sodium atoxyl-diazoamino-sulfoanthranilate first decomposes and then couples in vivo with the body protein to form the corresponding azoprotein and that therefore it is this compound, produced within the organism itself, which sensitizes.

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Selected References

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  1. Landsteiner K., van der Scheer J. ANAPHYLACTIC SHOCK BY AZODYES. J Exp Med. 1933 Mar 31;57(4):633–636. doi: 10.1084/jem.57.4.633. [DOI] [PMC free article] [PubMed] [Google Scholar]

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