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. 1939 Mar 31;69(4):499–505. doi: 10.1084/jem.69.4.499

THE ANTIBODY RESPONSE TO SWINE INFLUENZA

Carlos T Rosenbusch 1, Richard E Shope 1
PMCID: PMC2133654  PMID: 19870859

Abstract

Antibodies that neutralize swine influenza virus became detectible in the serum of swine on the 6th or 7th day after infection with swine influenza. Their appearance corresponded rather closely with clinical recovery. In swine with the milder filtrate disease, neutralizing antibodies did not appear until sometime between the 7th and 10th days. The maximum antibody titers ranged from 1:60 to 1:160 and were attained on from the 14th to the 27th days after infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Francis T., Shope R. E. NEUTRALIZATION TESTS WITH SERA OF CONVALESCENT OR IMMUNIZED ANIMALS AND THE VIRUSES OF SWINE AND HUMAN INFLUENZA. J Exp Med. 1936 Apr 30;63(5):645–653. doi: 10.1084/jem.63.5.645. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Lewis P. A., Shope R. E. SWINE INFLUENZA : II. A HEMOPHILIC BACILLUS FROM THE RESPIRATORY TRACT OF INFECTED SWINE. J Exp Med. 1931 Jul 31;54(3):361–371. doi: 10.1084/jem.54.3.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Shope R. E. IMMUNOLOGICAL RELATIONSHIP BETWEEN THE SWINE AND HUMAN INFLUENZA VIRUSES IN SWINE. J Exp Med. 1937 Jul 31;66(2):151–168. doi: 10.1084/jem.66.2.151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Shope R. E. STUDIES ON IMMUNITY TO SWINE INFLUENZA. J Exp Med. 1932 Sep 30;56(4):575–585. doi: 10.1084/jem.56.4.575. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Shope R. E. SWINE INFLUENZA : III. FILTRATION EXPERIMENTS AND ETIOLOGY. J Exp Med. 1931 Jul 31;54(3):373–385. doi: 10.1084/jem.54.3.373. [DOI] [PMC free article] [PubMed] [Google Scholar]

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