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. 1938 Oct 31;68(6):913–922. doi: 10.1084/jem.68.6.913

QUANTITATIVE STUDIES ON ANTIBODY PURIFICATION

III. THE REACTION OF DISSOCIATED ANTIBODY WITH SPECIFIC POLYSACCHARIDE, AND THE EFFECT OF FORMALDEHYDE

Michael Heidelberger 1, Pierre Grabar 1, Henry P Treffers 1
PMCID: PMC2133705  PMID: 19870826

Abstract

1. Tested quantitatively, antibody recovered by dissociation of specific precipitates from antipneumococcus sera reacts with homologous polysaccharide almost as does the antibody in the original sera. 2. The dissociation methods employed appear to yield a portion of all of the anticarbohydrates of differing reactivities in the sera, rather than a fraction of low or high reactivity. 3. The reversible inactivation of purified pneumococcus anticarbohydrate by formaldehyde is confirmed, and the failure of data on the formaldehyde-antibody reaction to permit a choice between alternative theories of specific precipitation is shown.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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