Abstract
A method has been devised to measure the spread of vital dyes in the skin of mice. Spread is greatly influenced by physiological and pathological changes which add fluid to the tissue or abstract it. Spread is greater in the quiet, living ear than in the ear of an animal just killed. It is equally considerable in the frankly edematous ears of living and dead animals, and not greater in either case than in normal, quiet tissues. During the early stages of edema formation on the other hand, dye spread is notably rapid. It is still greater in the ears of normal animals actively moving about, and is greatest in tissues subjected to very gently intermittent changes in external pressure. The significance of these findings is discussed.
Full Text
The Full Text of this article is available as a PDF (1.1 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hudack S. S., McMaster P. D. THE LYMPHATIC PARTICIPATION IN HUMAN CUTANEOUS PHENOMENA : A STUDY OF THE MINUTE LYMPHATICS OF THE LIVING SKIN. J Exp Med. 1933 Apr 30;57(5):751–774. doi: 10.1084/jem.57.5.751. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hudack S., McMaster P. D. I. THE PERMEABILITY OF THE WALL OF THE LYMPHATIC CAPILLARY. J Exp Med. 1932 Jul 31;56(2):223–238. doi: 10.1084/jem.56.2.223. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leathes J. B. Some Experiments on the Exchange of Fluid between the Blood and Tissues. J Physiol. 1895 Dec 30;19(1-2):1–14. doi: 10.1113/jphysiol.1895.sp000584. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D. CHANGES IN THE CUTANEOUS LYMPHATICS OF HUMAN BEINGS AND IN THE LYMPH FLOW UNDER NORMAL AND PATHOLOGICAL CONDITIONS. J Exp Med. 1937 Feb 28;65(3):347–372. doi: 10.1084/jem.65.3.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Hudack S. S. THE PARTICIPATION OF SKIN LYMPHATICS IN REPAIR OF THE LESIONS DUE TO INCISIONS AND BURNS. J Exp Med. 1934 Sep 30;60(4):479–501. doi: 10.1084/jem.60.4.479. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Hudack S. THE VESSELS INVOLVED IN HYDROSTATIC TRANSUDATION. J Exp Med. 1932 Feb 29;55(3):417–430. doi: 10.1084/jem.55.3.417. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parsons R. J., McMaster P. D. THE EFFECT OF THE PULSE UPON THE FORMATION AND FLOW OF LYMPH. J Exp Med. 1938 Aug 31;68(3):353–376. doi: 10.1084/jem.68.3.353. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Starling E. H. The Influence of Mechanical Factors on Lymph Production. J Physiol. 1894 Apr 17;16(3-4):224–267. doi: 10.1113/jphysiol.1894.sp000500. [DOI] [PMC free article] [PubMed] [Google Scholar]