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. 1938 Oct 31;68(6):837–852. doi: 10.1084/jem.68.6.837

CELLULAR REACTIONS TO TUBERCULO-PROTEINS COMPARED WITH THE REACTIONS TO TUBERCULO-LIPIDS

Florence R Sabin 1
PMCID: PMC2133709  PMID: 19870821

Abstract

1. Tuberculo-protein in solution induces the formation of monocytes in the normal animal and tubercles of epithelioid cells in that which is tuberculous. 2. Freshly precipitated tuberculo-proteins from the culture media and from the bacilli induce a moderate formation of epithelioid cells in normal animals, and more in the tuberculous. 3. Insoluble forms of tuberculo-protein induce complex tubercular tissue in normal animals. This action is enhanced in the tuberculous.

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Selected References

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