Skip to main content
PMC home page
The Journal of Hygiene logoLink to The Journal of Hygiene
. 1981 Dec;87(3):501–509. doi: 10.1017/s0022172400069758

Salmonella dublin infection of calves: use of small doses to simulate natural infection on the farm.

C Wray, W J Sojka
PMCID: PMC2134122  PMID: 7310128

Abstract

Small numbers of Salmonella dublin were used to infect calves in an attempt to simulate natural infection on the farm. Twenty calves were exposed to S. dublin by one or more of the following methods: Sucking cows which were excreting S. dublin in their faeces (less than 10(2)-10(5) organisms/g). Housing on S. dublin contaminated bedding. Drinking S. dublin contaminated water (10(2)-10(4) organisms/ml). During this experiment some calves were given therapeutic does of oxytetracycline. After exposure the calves were examined for faecal excretion of S. dublin (in some instances mouth swabs and blood samples were also examined) and for clinical signs of illness. Most of the calves became infected with S. dublin but excretion was usually sporadic and the numbers of salmonellas excreted were small. No clinical signs of salmonellosis were observed by S. dublin was isolated from one calf at post-mortem. Another six calves, dosed orally with either 10(6) or 10(8) S. dublin, showed signs of mild illness and although three calves had diarrhoea excretion of salmonellas was intermittent. S. dublin was isolated from one of these calves at post-mortem.

Full text

PDF
501

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aitken M. M., Hughes D. L., Jones P. W., Hall G. A., Collis K. A. Effects of intravenous Salmonella dublin on cattle at different stages of Fasciola hepatica infection. J Comp Pathol. 1978 Jul;88(3):433–442. doi: 10.1016/0021-9975(78)90048-8. [DOI] [PubMed] [Google Scholar]
  2. Forbes D., Oakley G. A., Mackenzie J. A. Experimental Salmonella dublin infection in calves. Vet Rec. 1977 Sep 17;101(12):220–224. doi: 10.1136/vr.101.12.220. [DOI] [PubMed] [Google Scholar]
  3. Hall G. A., Jones P. W. A study of the susceptibility of cattle to oral infection by salmonellas contained in raw sewage sludge. J Hyg (Lond) 1978 Jun;80(3):409–414. doi: 10.1017/s0022172400024864. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Jones P. W. Animal health today--problems of large livestock units. Disease hazards associated with slurry disposal. Br Vet J. 1980 Nov-Dec;136(6):529–542. doi: 10.1016/s0007-1935(17)32131-0. [DOI] [PubMed] [Google Scholar]
  5. Lander K. P., Gill K. P. Experimental infection of the bovine udder with Campylobacter coli/jejuni. J Hyg (Lond) 1980 Jun;84(3):421–428. doi: 10.1017/s0022172400026954. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Nazer A. H., Osborne A. D. Experimental Salmonella dublin infection in calves. Br Vet J. 1977 Jul-Aug;133(4):388–398. doi: 10.1016/s0007-1935(17)34040-x. [DOI] [PubMed] [Google Scholar]
  7. Rankin J. D., Taylor R. J. A study of some disease hazards which could be associated with the system of applying cattle slurry to pasture. Vet Rec. 1969 Nov 22;85(21):578–581. doi: 10.1136/vr.85.21.578. [DOI] [PubMed] [Google Scholar]
  8. Rankin J. D., Taylor R. J. The estimation of doses of Salmonella typhimurium suitable for the experimental production of disease in calves. Vet Rec. 1966 May 21;78(21):706–707. doi: 10.1136/vr.78.21.706. [DOI] [PubMed] [Google Scholar]
  9. Smith H. W., Jones J. E. Observations on experimental oral infection with Salmonella dublin in calves and Salmonella choleraesuis in pigs. J Pathol Bacteriol. 1967 Jan;93(1):141–156. doi: 10.1002/path.1700930114. [DOI] [PubMed] [Google Scholar]
  10. Sojka W. J., Thomson P. D., Hudson E. B. Excretion of Salmonella dublin by adult bovine carriers. Br Vet J. 1974 Sep-Oct;130(5):482–488. doi: 10.1016/s0007-1935(17)35791-3. [DOI] [PubMed] [Google Scholar]
  11. Taylor R. J., Burrows M. R. The survival of Escherichia coli and Salmonella dublin in slurry on pasture and the infectivity of S. dublin for grazing calves. Br Vet J. 1971 Nov;127(11):536–543. doi: 10.1016/s0007-1935(17)37287-1. [DOI] [PubMed] [Google Scholar]
  12. Wray C., Dawson M., Afshar A., Lucas M. Experimental Escherichia coli and rotavirus infection in lambs. Res Vet Sci. 1981 May;30(3):379–381. [PubMed] [Google Scholar]
  13. Wray C., Morris J. A., Sojka W. J. A comparison of indirect hemagglutination tests and serum agglutination tests for the serological diagnosis of Salmonella dublin infection in cattle. Br Vet J. 1975 Nov-Dec;131(6):727–737. doi: 10.1016/s0007-1935(17)35145-x. [DOI] [PubMed] [Google Scholar]
  14. Wray C., Sojka W. J. Experimental Salmonella typhimurium infection in calves. Res Vet Sci. 1978 Sep;25(2):139–143. [PubMed] [Google Scholar]
  15. de Jong H., Ekdahl M. O. Salmonellosis in calves--the effect of dose rate and other factors on transmission. N Z Vet J. 1965 Jun;13(3):59–64. doi: 10.1080/00480169.1965.33598. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Hygiene are provided here courtesy of Cambridge University Press

RESOURCES