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. 1982 Oct;89(2):295–301. doi: 10.1017/s0022172400070820

Field trials of second-generation anticoagulants against difenacoum-resistant Norway rat populations.

J H Greaves, D S Shepherd, R Quy
PMCID: PMC2134219  PMID: 7130704

Abstract

Trials of rodenticidal baits containing 50 p.p.m. difenacoum, 50 p.p.m. bromadiolone or 20 p.p.m. brodifacoum were carried out on farmsteads against populations of Rattus norvegicus containing difenacoum-resistant individuals. Six difenacoum treatments failed in 14--42 days of baiting. Two treatments with bromadiolone succeeded in 23 and 33 days, but four further treatments lasting 35--56 days failed to eradicate the populations. Brodifacoum gave virtually complete control of six populations in 21--73 days and of the ten residual populations left behind by the other two compounds, after baiting for a further 11--85 days. The performance of both bromadiolone and brodifacoum was well below that reported by previous investigators, indicating the possibility of low-grade resistance to these compounds in the difenacoum-resistant strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Drummond D. C., Rennison B. D. The detection of rodent resistance to anticoagulants. Bull World Health Organ. 1973;48(2):239–242. [PMC free article] [PubMed] [Google Scholar]
  2. Redfern R., Gill J. E., Hadler M. R. Laboratory evaluation of WBA 8119 as a rodenticide for use against warfarin-resistant and non-resistant rats and mice. J Hyg (Lond) 1976 Dec;77(3):419–426. doi: 10.1017/s0022172400055807. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Redfern R., Gill J. E. Laboratory evaluation of bromadiolone as a rodenticide for use against warfarin-resistant and non-resistant rats and mice. J Hyg (Lond) 1980 Apr;84(2):263–268. doi: 10.1017/s0022172400026760. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Rennison B. D., Dubock A. C. Field trials of WBA 8119 (PP 581, brodifacoum) against warfarin-resistant infestations of Rattus norvegicus. J Hyg (Lond) 1978 Feb;80(1):77–82. doi: 10.1017/s0022172400053419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Richards C. G. Field trials of bromadiolone against infestations of warfarin-resistant Rattus norvegicus. J Hyg (Lond) 1981 Jun;86(3):363–367. doi: 10.1017/s0022172400069126. [DOI] [PMC free article] [PubMed] [Google Scholar]

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