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. 1982 Dec;89(3):439–448. doi: 10.1017/s002217240007100x

Legionella infections in Scotland.

R J Fallon
PMCID: PMC2134247  PMID: 7153509

Abstract

Four thousand two hundred and thirty-five sera from 2794 patients and 740 sera from 735 tourists domiciled in Scotland recently returned from abroad were examined between 1977 and 1981 for antibodies to Legionella pneumophila and related organisms. In addition, specimens were examined from some patients for cultural or serological demonstration of these organisms in lung or sputum. One hundred and ten cases were diagnosed, 104 serologically, five by immunofluorescence demonstration of legionellas in lung biopsy or autopsy specimens and L. pneumophila serogroup 1 was isolated from a further case. Of patients with pneumonia 6.7% showed evidence of legionella infection. Only 0.4% of healthy tourists had antibodies at a level of greater than or equal to 256. The majority of cases occurred in patients aged 50-69 and in 36 patients the infection was acquired outside the United Kingdom. Males predominated, the male: female ratio being 2: 1. Cases were less frequent in the first quarter of the year but those originating in Scotland were equally common in the remaining three quarters. Cases with disease acquired abroad added to indigenous cases resulted in a summer peak occurring in July, August and September. There were no outbreaks of legionellosis in Scotland.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boyd J. F., Buchanan W. M., MacLeod T. I., Dunn R. I., Weir W. P. Pathology of five Scottish deaths from pneumonic illnesses acquired in Spain due to Legionnaires' disease agent. J Clin Pathol. 1978 Sep;31(9):809–816. doi: 10.1136/jcp.31.9.809. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. England A. C., 3rd, Fraser D. W., Plikaytis B. D., Tsai T. F., Storch G., Broome C. V. Sporadic legionellosis in the United States: the first thousand cases. Ann Intern Med. 1981 Feb;94(2):164–170. doi: 10.7326/0003-4819-94-2-164. [DOI] [PubMed] [Google Scholar]
  3. Fallon R. J., Abraham W. H. Detecting legionnaires' disease. Lancet. 1978 Dec 16;2(8103):1318–1318. doi: 10.1016/s0140-6736(78)92091-3. [DOI] [PubMed] [Google Scholar]
  4. Fallon R. J., Abraham W. H. Polyvalent heat-killed antigen for the diagnosis of infection with Legionella pneumophila. J Clin Pathol. 1982 Apr;35(4):434–438. doi: 10.1136/jcp.35.4.434. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Fallon R. J., Abraham W. H. Scottish experience with the serologic diagnosis of Legionnaires' disease. Ann Intern Med. 1979 Apr;90(4):684–686. doi: 10.7326/0003-4819-90-4-684. [DOI] [PubMed] [Google Scholar]
  6. Harrison T. G., Taylor A. G. Diagnosis of Legionella pneumophila infections by means of formolised yolk sac antigens. J Clin Pathol. 1982 Feb;35(2):211–214. doi: 10.1136/jcp.35.2.211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Horwitz M. A., Silverstein S. C. Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Invest. 1980 Sep;66(3):441–450. doi: 10.1172/JCI109874. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lawson J. H. Legionnaires' Disease--the Benidorm episode. Scott Med J. 1978 Apr;23(2):121–124. doi: 10.1177/003693307802300204. [DOI] [PubMed] [Google Scholar]
  9. Lees A. W., Tyrrell W. F., Boyd J. F. Legionnaire's disease. Lancet. 1977 Dec 3;2(8049):1187–1187. doi: 10.1016/s0140-6736(77)91588-4. [DOI] [PubMed] [Google Scholar]
  10. Macrae A. D., Appleton P. N., Laverick A. Legionnaires' disease in Nottingham, England. Ann Intern Med. 1979 Apr;90(4):580–583. doi: 10.7326/0003-4819-90-4-580. [DOI] [PubMed] [Google Scholar]
  11. McDade J. E., Shepard C. C., Fraser D. W., Tsai T. R., Redus M. A., Dowdle W. R. Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease. N Engl J Med. 1977 Dec 1;297(22):1197–1203. doi: 10.1056/NEJM197712012972202. [DOI] [PubMed] [Google Scholar]
  12. Reid D., Grist N. R., Nájera R. Illness associated with "package tours": a combined Spanish-Scottish study. Bull World Health Organ. 1978;56(1):117–122. [PMC free article] [PubMed] [Google Scholar]
  13. Snowman W. J., Holtzhauer F. J., Halpin T. J., Correa-Villasenor A. The role of indoor and outdoor occupations in the seroepidemiology of Legionella pneumophila. J Infect Dis. 1982 Feb;145(2):275–275. doi: 10.1093/infdis/145.2.275. [DOI] [PubMed] [Google Scholar]
  14. Tobin J. O., Bartlett C. L., Waitkins S. A., Barrow G. I., Macrae A. D., Taylor A. G., Fallon R. J., Lynch F. R. Legionnaires' disease: further evidence to implicate water storage and distribution systems as sources. Br Med J (Clin Res Ed) 1981 Feb 14;282(6263):573–573. doi: 10.1136/bmj.282.6263.573. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Wilkinson H. W., Fikes B. J., Cruce D. D. Indirect immunofluorescence test for serodiagnosis of Legionnaires disease: evidence for serogroup diversity of Legionnaires disease bacterial antigens and for multiple specificity of human antibodies. J Clin Microbiol. 1979 Mar;9(3):379–383. doi: 10.1128/jcm.9.3.379-383.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]

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