Figure 3.

Endogenous enzyme activities of MMP-9, MMP-2, and uPA for oxygenated and hypoxic PC-3 cells grown adherently on Biosilon beads (PC-3_Bb) in the absence and presence of HUVECs on the surface of the ECM gel. Whenever the concentration standard resulted in a usable standard curve, concentrations were calculated otherwise the results were reported as absorbance at 405 nm per cell (δAbs₄₀₅/cell) which is proportional to the enzyme activity per cell. A summary and additional data for the different conditions can be found in Table W1 and Figure W1. Each panel represents an independent experiment.