Abstract
The electrophoretic patterns of the sera and urine of two cases of lipoid nephrosis have been obtained and have been compared with a typical pattern of normal serum. The patterns of the pathological sera deviated widely from the normal, indicating relatively low albumin and high globulin content. The comparison of the patterns of nephrotic sera cleared by centrifugation and by ether extraction shows that a large portion of the β globulin consisted of a labile lipo-protein. The pattern of the nephrotic urine proteins resembled that of normal serum, with, however, significant differences.
Full Text
The Full Text of this article is available as a PDF (286.8 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bourdillon J. OSMOTIC PRESSURE STUDY OF PROTEIN FRACTIONS IN NORMAL AND IN NEPHROTIC SUBJECTS. J Exp Med. 1939 May 31;69(6):819–831. doi: 10.1084/jem.69.6.819. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Longsworth L. G., Shedlovsky T., Macinnes D. A. ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD SERUM AND PLASMA. J Exp Med. 1939 Sep 30;70(4):399–413. doi: 10.1084/jem.70.4.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stenhagen E. Electrophoresis of human blood plasma: Electrophoretic properties of fibrinogen. Biochem J. 1938 Apr;32(4):714–718. doi: 10.1042/bj0320714. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tiselius A. Electrophoresis of serum globulin: Electrophoretic analysis of normal and immune sera. Biochem J. 1937 Sep;31(9):1464–1477. doi: 10.1042/bj0311464. [DOI] [PMC free article] [PubMed] [Google Scholar]