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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1940 Jun 30;72(1):91–97. doi: 10.1084/jem.72.1.91

THE RELATIONSHIP OF SULFAPYRIDINE, NICOTINIC ACID, AND COENZYMES TO THE GROWTH OF STAPHYLOCOCCUS AUREUS

Randolph West 1, Alvin F Coburn 1
PMCID: PMC2135015  PMID: 19871010

Abstract

Our studies indicate that sulfapyridine modifies the normal metabolism of a bacterium. Coenzymes inhibit the effect of sulfapyridine on the growth of staphylococcus in Knight's medium. Nicotinic acid does not interfere with the action of sulfapyridine under the same conditions. The possible relation of sulfapyridine, nicotinic acid, and coenzymes in relation to bacterial growth is discussed.

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Selected References

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