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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1940 Jun 30;72(1):69–77. doi: 10.1084/jem.72.1.69

ENCEPHALOMYELITIS OF MICE

II. A METHOD FOR THE MEASUREMENT OF VIRUS ACTIVITY

Sven Gard 1
PMCID: PMC2135016  PMID: 19871008

Abstract

In a study of mouse encephalomyelitis the following observations were made:— 1. A definite relationship exists between the amount of virus inoculated intracerebrally and the length of the incubation period. 2. The reciprocal of the incubation period was found to be approximately proportionate to the logarithm of the amount of virus inoculated. The relationship can, therefore, be given a simple mathematical form. 3. This fact provides a basis for a new method for measurement of the activity of mouse encephalomyelitis virus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Horsfall F. L. NEUTRALIZATION OF EPIDEMIC INFLUENZA VIRUS : THE LINEAR RELATIONSHIP BETWEEN THE QUANTITY OF SERUM AND THE QUANTITY OF VIRUS NEUTRALIZED. J Exp Med. 1939 Jul 31;70(2):209–222. doi: 10.1084/jem.70.2.209. [DOI] [PMC free article] [PubMed] [Google Scholar]
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