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. 1940 Mar 31;71(4):539–550. doi: 10.1084/jem.71.4.539

THE SIGNIFICANCE OF M AND T ANTIGENS IN THE CROSS REACTIONS BETWEEN CERTAIN TYPES OF GROUP A HEMOLYTIC STREPTOCOCCI

Rebecca C Lancefield 1
PMCID: PMC2135090  PMID: 19870979

Abstract

In any one strain the occurrence of the previously recognized type-specific protein, M, is usually completely correlated with the presence of the recently recognized type-specific antigen, T. Strain C203 is exceptional in having the T substance of type 1 as well as the two type-specific antigens, M and T, characteristic of type 3. It does not have the M antigen of type 1. While other strains with similar antigenic peculiarities have not been encountered, it is probable that they occur, and the existence of such anomalies must be suspected when unusual serological reactions occur.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hirst G. K., Lancefield R. C. ANTIGENIC PROPERTIES OF THE TYPE-SPECIFIC SUBSTANCE DERIVED FROM GROUP A HEMOLYTIC STREPTOCOCCI. J Exp Med. 1939 Feb 28;69(3):425–445. doi: 10.1084/jem.69.3.425. [DOI] [PMC free article] [PubMed] [Google Scholar]
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