Abstract
Methods have been devised to bring microscopic amounts of fluid into contact with cutaneous connective tissue, under pressure or without pressure, in such a manner that it enters neither blood capillaries nor lymphatics directly. The take-up of fluid brought into contact with the tissues in this way has been measured and its characteristics studied. Elaborate control tests, here described and discussed, have indicated the possible errors in the employment of these methods. Locke's or Tyrode's solutions brought into contact with the cutaneous tissues, by the method described and at atmospheric pressure, pass into the tissue intermittently. Forced into the skin by pressures of 1.0 to 2.0 cm. of water the take-up is still intermittent in character. From this it follows that either the absorption of interstitial fluid from localized regions is periodic or the movements of interstitial fluid are influenced by intermittent physiological changes.
Full Text
The Full Text of this article is available as a PDF (2.1 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hudack S. S., McMaster P. D. THE LYMPHATIC PARTICIPATION IN HUMAN CUTANEOUS PHENOMENA : A STUDY OF THE MINUTE LYMPHATICS OF THE LIVING SKIN. J Exp Med. 1933 Apr 30;57(5):751–774. doi: 10.1084/jem.57.5.751. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hudack S., McMaster P. D. I. THE PERMEABILITY OF THE WALL OF THE LYMPHATIC CAPILLARY. J Exp Med. 1932 Jul 31;56(2):223–238. doi: 10.1084/jem.56.2.223. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hudack S., McMaster P. D. THE GRADIENT OF PERMEABILITY OF THE SKIN VESSELS AS INFLUENCED BY HEAT, COLD, AND LIGHT. J Exp Med. 1932 Feb 29;55(3):431–439. doi: 10.1084/jem.55.3.431. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D. CHANGES IN THE CUTANEOUS LYMPHATICS OF HUMAN BEINGS AND IN THE LYMPH FLOW UNDER NORMAL AND PATHOLOGICAL CONDITIONS. J Exp Med. 1937 Feb 28;65(3):347–372. doi: 10.1084/jem.65.3.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Hudack S. S. THE PARTICIPATION OF SKIN LYMPHATICS IN REPAIR OF THE LESIONS DUE TO INCISIONS AND BURNS. J Exp Med. 1934 Sep 30;60(4):479–501. doi: 10.1084/jem.60.4.479. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Hudack S. II. INDUCED ALTERATIONS IN THE PERMEABILITY OF THE LYMPHATIC CAPILLARY. J Exp Med. 1932 Jul 31;56(2):239–253. doi: 10.1084/jem.56.2.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Hudack S., Rous P. THE RELATION OF HYDROSTATIC PRESSURE TO THE GRADIENT OF CAPILLARY PERMEABILITY. J Exp Med. 1932 Jan 31;55(2):203–221. doi: 10.1084/jem.55.2.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Hudack S. THE VESSELS INVOLVED IN HYDROSTATIC TRANSUDATION. J Exp Med. 1932 Feb 29;55(3):417–430. doi: 10.1084/jem.55.3.417. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Parsons R. J. PHYSIOLOGICAL CONDITIONS EXISTING IN CONNECTIVE TISSUE : I. TTHE METHOD OF INTERSTITIAL SPREAD OF VITAL DYES. J Exp Med. 1939 Jan 31;69(2):247–264. doi: 10.1084/jem.69.2.247. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Parsons R. J. PHYSIOLOGICAL CONDITIONS EXISTING IN CONNECTIVE TISSUE : II. THE STATE OF THE FLUID IN THE INTRADERMAL TISSUE. J Exp Med. 1939 Jan 31;69(2):265–282. doi: 10.1084/jem.69.2.265. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D., Parsons R. J. THE EFFECT OF THE PULSE ON THE SPREAD OF SUBSTANCES THROUGH TISSUES. J Exp Med. 1938 Aug 31;68(3):377–400. doi: 10.1084/jem.68.3.377. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMaster P. D. THE LYMPHATICS AND LYMPH FLOW IN THE EDEMATOUS SKIN OF HUMAN BEINGS WITH CARDIAC AND RENAL DISEASE. J Exp Med. 1937 Feb 28;65(3):373–392. doi: 10.1084/jem.65.3.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parsons R. J., McMaster P. D. NORMAL AND PATHOLOGICAL FACTORS INFLUENCING THE SPREAD OF A VITAL DYE IN THE CONNECTIVE TISSUE. J Exp Med. 1938 Oct 31;68(6):869–890. doi: 10.1084/jem.68.6.869. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parsons R. J., McMaster P. D. THE EFFECT OF THE PULSE UPON THE FORMATION AND FLOW OF LYMPH. J Exp Med. 1938 Aug 31;68(3):353–376. doi: 10.1084/jem.68.3.353. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schmitt F. O., Schmitt O. H. A VACUUM TUBE METHOD OF TEMPERATURE CONTROL. Science. 1931 Mar 13;73(1889):289–290. doi: 10.1126/science.73.1889.289. [DOI] [PubMed] [Google Scholar]