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. 1941 Mar 31;73(4):487–492. doi: 10.1084/jem.73.4.487

A NEW GROWTH FACTOR REQUIRED BY CERTAIN HEMOLYTIC STREPTOCOCCI

D W Woolley 1
PMCID: PMC2135140  PMID: 19871092

Abstract

A new factor essential for the growth of hemolytic streptococci of Lancefield's group A has been demonstrated. It has not been possible to identify this factor with any other known growth factor. The active substance occurred in liver as a water-soluble, alcohol-insoluble, non-dialyzable material. It could be rendered dialyzable by treatment in strong alcohol with HCl, but not by many less drastic procedures. The most active concentrates prepared gave a maximal effect when approximately 10 gamma per cc. were added.

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Selected References

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  1. Snell E. E., Peterson W. H. Growth Factors for Bacteria: X. Additional Factors Required by Certain Lactic Acid Bacteria. J Bacteriol. 1940 Mar;39(3):273–285. doi: 10.1128/jb.39.3.273-285.1940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Woolley D. W., Hutchings B. L. Synthetic Media for Culture of Certain Hemolytic Streptococci. J Bacteriol. 1940 Mar;39(3):287–296. doi: 10.1128/jb.39.3.287-296.1940. [DOI] [PMC free article] [PubMed] [Google Scholar]

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