Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1942 Jan 31;75(2):151–164. doi: 10.1084/jem.75.2.151

THE LS-ANTIGEN OF VACCINIA

I. INHIBITION OF L- AND S-ANTIBODIES BY SUBSTANCES IN TREATED VACCINE DERMAL FILTRATE

Joseph E Smadel 1, Thomas M Rivers 1
PMCID: PMC2135236  PMID: 19871173

Abstract

Experimental data are presented which may be interpreted as follows. The heat-labile (L) and heat-stable (S) antigens of vaccinia occur in nature as a complex consisting of a single substance with two serologically active parts, each of which may be degraded independently of the other.

Full Text

The Full Text of this article is available as a PDF (775.9 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Craigie J., Wishart F. O. STUDIES ON THE SOLUBLE PRECIPITABLE SUBSTANCES OF VACCINIA : II. THE SOLUBLE PRECIPITABLE SUBSTANCES OF DERMAL VACCINE. J Exp Med. 1936 Oct 31;64(5):819–830. doi: 10.1084/jem.64.5.819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Parker R. F. IMMUNOLOGICAL STUDIES OF A HEAT-STABLE SUBSTANCE ISOLATED FROM TISSUES INFECTED WITH VACCINE VIRUS. J Exp Med. 1938 Feb 28;67(3):361–367. doi: 10.1084/jem.67.3.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Shedlovsky T., Smadel J. E. THE LS-ANTIGEN OF VACCINIA : II. ISOLATION OF A SINGLE SUBSTANCE CONTAINING BOTH L- AND S-ACTIVITY. J Exp Med. 1942 Jan 31;75(2):165–178. doi: 10.1084/jem.75.2.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Smadel J. E., Lavin G. I., Dubos R. J. SOME CONSTITUENTS OF ELEMENTARY BODIES OF VACCINIA. J Exp Med. 1940 Feb 29;71(3):373–389. doi: 10.1084/jem.71.3.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Smadel J. E., Ward S. M., Rivers T. M. INFECTIOUS MYXOMATOSIS OF RABBITS : II. DEMONSTRATION OF A SECOND SOLUBLE ANTIGEN ASSOCIATED WITH THE DISEASE. J Exp Med. 1940 Jul 31;72(2):129–138. doi: 10.1084/jem.72.2.129. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES