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. 1943 Oct 1;78(4):241–253. doi: 10.1084/jem.78.4.241

LABORATORY TRANSMISSION OF ST. LOUIS ENCEPHALITIS VIRUS BY THREE GENERA OF MOSQUITOES

W McD Hammon 1, W C Reeves 1
PMCID: PMC2135400  PMID: 19871325

Abstract

1. St. Louis virus has been successfully transmitted in the laboratory by the following 9 species of mosquitoes from 3 genera: Culex tarsalis, Culex pipiens, Culex coronator, Aedes lateralis, Aedes taeniorhynchus, Aedes vexans, Aedes nigromaculis, Theobaldia incidens, and Theobaldia inornata. 2. Though transmission has not been demonstrated, survival of the virus for more than a few days was shown to occur in Culex quinquefasciatus, Culex stigmatosoma, Psorophora ciliata, and Anopheles maculipennis freeborni. 3. In experiments with Culex tarsalis, infection occurred from feeding on chickens and ducks which had been previously inoculated by the subcutaneous route. After an incubation period these mosquitoes infected other chickens and virus was in turn demonstrated in the blood of these. This is interpreted as proof that fowl may serve as reservoirs of virus in nature. Since mosquitoes have been repeatedly found naturally infected with St. Louis virus and epidemiologic evidence supports their incrimination, their rôle as vectors is now established. The fully incriminated species is Culex tarsalis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hammon W. M., Reeves W. C., Brookman B., Izumi E. M., Gjullin C. M. ISOLATION OF THE VIRUSES OF WESTERN EQUINE AND ST. LOUIS ENCEPHALITIS FROM CULEX TARSALIS MOSQUITOES. Science. 1941 Oct 3;94(2440):328–330. doi: 10.1126/science.94.2440.328. [DOI] [PubMed] [Google Scholar]
  2. Hammon W. M., Reeves W. C., Gray M. Mosquito Vectors and Inapparent Animal Reservoirs of St. Louis and Western Equine Encephalitis Viruses. Am J Public Health Nations Health. 1943 Mar;33(3):201–207. doi: 10.2105/ajph.33.3.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Merrill M. H., Tenbroeck C. THE TRANSMISSION OF EQUINE ENCEPHALOMYELITIS VIRUS BY AEDES AEGYPTI. J Exp Med. 1935 Oct 31;62(5):687–695. doi: 10.1084/jem.62.5.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Webster L. T., Clow A. D., Bauer J. H. EXPERIMENTAL STUDIES ON ENCEPHALITIS : III. SURVIVAL OF ENCEPHALITIS VIRUS (ST. LOUIS TYPE) IN ANOPHELES QUADRIMACULATUS. J Exp Med. 1935 Mar 31;61(4):479–487. doi: 10.1084/jem.61.4.479. [DOI] [PMC free article] [PubMed] [Google Scholar]

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