Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1944 Feb 1;79(2):129–135. doi: 10.1084/jem.79.2.129

DEPRESSION OF ANAEROBIC GLYCOLYSIS OF EMBRYONIC TISSUE BY WESTERN STRAIN OF EQUINE ENCEPHALOMYELITIS VIRUS. PREVENTION OF THIS EFFECT BY SPECIFIC IMMUNE SERUM

Joseph Victor 1, C H Huang 1
PMCID: PMC2135444  PMID: 19871358

Abstract

Studies were made on the effect of mixing the Western strain of equine encephalomyelitis virus (W.E.E.) and embryonic tissue on the rate of anaerobic glycolysis of the tissue. Whole chick embryo, chick embryo from which brain and spinal cord had been removed, and embryonic skeletal muscle were employed. 1. W.E.E. virus depressed the rate of anaerobic glycolysis of embryonic tissues within 2 days after its addition to the tissue. The decrease in anaerobic glycolysis varied from 17 to 82 per cent and was apparent 2 to 4 days after the addition of the virus. No significant effect of the virus was observed 4 hours and 6 days after mixing it with the tissue. 2. Anti-W.E.E. immune serum prevented the inhibiting action of W.E.E. virus on the anaerobic glycolysis of embryonic skeletal muscle.

Full Text

The Full Text of this article is available as a PDF (336.3 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Huang C. H. FURTHER STUDIES ON THE TITRATION AND NEUTRALIZATION OF THE WESTERN STRAIN OF EQUINE ENCEPHALOMYELITIS VIRUS IN TISSUE CULTURE. J Exp Med. 1943 Aug 1;78(2):111–126. doi: 10.1084/jem.78.2.111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Racker E., Kabat H. THE METABOLISM OF THE CENTRAL NERVOUS SYSTEM IN EXPERIMENTAL POLIOMYELITIS. J Exp Med. 1942 Dec 1;76(6):579–585. doi: 10.1084/jem.76.6.579. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES