Abstract
The kinetics of the hemolytic reaction effected by the hemolysin of Clostridium septicum, strain 44, has been studied with regard to the effect of concentration, temperature, and hydrogen ion concentration on the rate of the hemolytic reaction. The kinetics of hemolysis was found to resemble in several respects that of enzyme-catalyzed reactions, but differed in the absence of a clearly defined pH optimum. Attention is drawn to differences between the hemolytic system studied and certain other hemolytic systems.
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Selected References
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- Bernheimer A. W. PARALLELISM IN THE LETHAL AND HEMOLYTIC ACTIVITY OF THE TOXIN OF CLOSTRIDIUM SEPTICUM. J Exp Med. 1944 Oct 1;80(4):309–320. doi: 10.1084/jem.80.4.309. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bernheimer A. W., Technical Assistance of Margaret T. Spencer NUTRITIONAL REQUIREMENTS AND FACTORS AFFECTING THE PRODUCTION OF TOXIN OF CLOSTRIDIUM SEPTICUM. J Exp Med. 1944 Oct 1;80(4):321–331. doi: 10.1084/jem.80.4.321. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Herbert D., Todd E. W. Purification and properties of a haemolysin produced by group A haemolytic streptococci (streptolysin O). Biochem J. 1941 Nov;35(10-11):1124–1139. doi: 10.1042/bj0351124. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Macfarlane M. G., Knight B. C. The biochemistry of bacterial toxins: The lecithinase activity of Cl. welchii toxins. Biochem J. 1941 Sep;35(8-9):884–902. doi: 10.1042/bj0350884. [DOI] [PMC free article] [PubMed] [Google Scholar]