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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1946 Mar 31;83(4):321–328.

MOUSE-PROTECTIVE TITERS OF SERA OF VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES

Annabel W Walter 1, Edna L Schenkein 1, Wheelan D Sutliff 1
PMCID: PMC2135601  PMID: 19871533

Abstract

1. Sera of human subjects immunized with pneumococci or their type-specific polysaccharides showed type-specific antibody by mouse protection tests as well as on determinations of the specifically precipitable nitrogen. 2. The ratio, mouse-protective units to antibody nitrogen, was less in human sera of low potency than in more potent human or animal sera.

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Selected References

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