Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1947 Jan 1;85(1):65–76. doi: 10.1084/jem.85.1.65

DISINFECTION OF CLOUDS OF MENINGOPNEUMONITIS AND PSITTACOSIS VIRUSES WITH TRIETHYLENE GLYCOL VAPOR

Theodor Rosebury 1, Gordon Meiklejohn 1, Lawrence C Kingsland 1, Martin H Boldt 1
PMCID: PMC2135670  PMID: 19871600

Abstract

1. Triethylene glycol in excess of saturation, introduced as a vapor into a cloud chamber in which a dynamic cloud of either meningopneumonitis virus or psittacosis virus was developed simultaneously with, or in most instances subsequently to, the glycol cloud, induced distinct reduction in concentration of air-home virus, as measured both by cloud sampling in capillary impingers and by exposure of mice to the cloud. The relative humidity in the chamber was held between 35 and about 60 per cent. 2. Reduction of virus concentration in samplers, in glycol runs as compared with controls, ranged from 0 to 93 per cent (average, 62 per cent). 3. Reduction of infective response in mice, based on counts of focal lesions on lung surfaces, ranged from 55 to 98 per cent (average 73 per cent).

Full Text

The Full Text of this article is available as a PDF (683.5 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Puck T. T., Robertson O. H., Lemon H. M. THE BACTERICIDAL ACTION OF PROPYLENE GLYCOL VAPOR ON MICROORGANISMS SUSPENDED IN AIR : II. THE INFLUENCE OF VARIOUS FACTORS ON THE ACTIVITY OF THE VAPOR. J Exp Med. 1943 Nov 1;78(5):387–406. doi: 10.1084/jem.78.5.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Robertson O. H., Bigg E., Miller B. F., Baker Z. STERILIZATION OF AIR BY CERTAIN GLYCOLS EMPLOYED AS AEROSOLS. Science. 1941 Feb 28;93(2409):213–214. doi: 10.1126/science.93.2409.213. [DOI] [PubMed] [Google Scholar]
  3. Robertson O. H., Bigg E., Puck T. T., Miller B. F., Technical Assistance of Elizabeth A. Appell THE BACTERICIDAL ACTION OF PROPYLENE GLYCOL VAPOR ON MICROORGANISMS SUSPENDED IN AIR. I. J Exp Med. 1942 Jun 1;75(6):593–610. doi: 10.1084/jem.75.6.593. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Robertson O. H., Loosli C. G., Puck T. T., Bigg E., Miller B. F. THE PROTECTION OF MICE AGAINST INFECTION WITH AIR-BORNE INFLUENZA VIRUS BY MEANS OF PROPYLENE GLYCOL VAPOR. Science. 1941 Dec 26;94(2452):612–613. doi: 10.1126/science.94.2452.612. [DOI] [PubMed] [Google Scholar]
  5. Robertson O. H., Puck T. T., Lemon H. F., Loosli C. G. THE LETHAL EFFECT OF TRIETHYLENE GLYCOL VAPOR ON AIR-BORNE BACTERIA AND INFLUENZA VIRUS. Science. 1943 Feb 5;97(2510):142–144. doi: 10.1126/science.97.2510.142. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES