Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1948 Apr 1;87(4):295–300. doi: 10.1084/jem.87.4.295

IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS

VI. THE CROSS-REACTION BETWEEN TYPE XIV ANTIPNEUMOCOCCAL HORSE SERUM AND PURIFIED BLOOD GROUP A, B, AND O SUBSTANCES FROM HOG AND HUMAN SOURCES

Elvin A Kabat 1, Aaron Bendich 1, Ada E Bezer 1, Vesta Knaub 1
PMCID: PMC2135777  PMID: 18904215

Abstract

Purified blood group A, B, and O substances from hog and human sources precipitate with Type XIV antipneumococcal horse serum and provide an explanation for the observation that Type XIV antibody agglutinates human erythrocytes of all four major blood groups. Individual preparations of A substance or O substance from either species vary in their capacity to precipitate Type XIV antibody although the hog A substances did not differ in potency toward anti-A. Similarly, no correlation between A activity and reactivity with Type XIV antibody could be found among the human A substances.

Full Text

The Full Text of this article is available as a PDF (319.7 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bendich A., Kabat E. A., Bezer A. E., With an Appendix by Erwin Brand, Ph.D., and Leo J. Saidel IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : III. PROPERTIES OF PURIFIED BLOOD GROUP A SUBSTANCES FROM INDIVIDUAL HOG STOMACH LININGS. J Exp Med. 1946 May 31;83(6):485–497. [PMC free article] [PubMed] [Google Scholar]
  2. Heidelberger M., Kabat E. A., Mayer M. A FURTHER STUDY OF THE CROSS REACTION BETWEEN THE SPECIFIC POLYSACCHARIDES OF TYPES III AND VIII PNEUMOCOCCI IN HORSE ANTISERA. J Exp Med. 1942 Jan 1;75(1):35–47. doi: 10.1084/jem.75.1.35. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Heidelberger M., Kabat E. A., Shrivastava D. L. A QUANTITATIVE STUDY OF THE CROSS REACTION OF TYPES III AND VIII PNEUMOCOCCI IN HORSE AND RABBIT ANTISERA. J Exp Med. 1937 Mar 31;65(4):487–496. doi: 10.1084/jem.65.4.487. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Heidelberger M., Macpherson C. F. QUANTITATIVE MICRO-ESTIMATION OF ANTIBODIES IN THE SERA OF MAN AND OTHER ANIMALS. Science. 1943 Apr 30;97(2522):405–406. doi: 10.1126/science.97.2522.405. [DOI] [PubMed] [Google Scholar]
  5. Kabat E. A., Bendich A., Bezer A. E., Beiser S. M. IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : IV. PREPARATION OF BLOOD GROUP A SUBSTANCES FROM HUMAN SOURCES AND A COMPARISON OF THEIR CHEMICAL AND IMMUNOCHEMICAL PROPERTIES WITH THOSE OF THE BLOOD GROUP A SUBSTANCE FROM HOG STOMACH. J Exp Med. 1947 May 31;85(6):685–699. doi: 10.1084/jem.85.6.685. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Kabat E. A., Bendich A., Bezer A. E. IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : II. PROPERTIES OF THE BLOOD GROUP A SUBSTANCE FROM POOLS OF HOO STOMACHS AND OF SPECIFIC PRECIPITATES COMPOSED OF "A" SUBSTANCE AND HOMOLOGOUS HUMAN ANTIBODY. J Exp Med. 1946 May 31;83(6):477–484. [PMC free article] [PubMed] [Google Scholar]
  7. Markham R. A steam distillation apparatus suitable for micro-Kjeldahl analysis. Biochem J. 1942 Dec;36(10-12):790–791. doi: 10.1042/bj0360790. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES