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. 1948 May 1;87(5):385–410. doi: 10.1084/jem.87.5.385

THE INHIBITORY EFFECT OF POLYSACCHARIDE ON MUMPS VIRUS MULTIPLICATION

Harold S Ginsberg 1, Walther F Goebel 1, Frank L Horsfall Jr 1
PMCID: PMC2135788  PMID: 18912891

Abstract

Polysaccharides derived from type-specific Friedländer bacilli cause inhibition of the multiplication of mumps virus in the allantoic sac of the chick embryo. As little as 5 µg. of polysaccharide is effective as an inhibitor. Inhibition of multiplication is obtained when polysaccharide is injected as long as 4 days after inoculation of virus. Chemical studies have shown that the structural configurations of the polysaccharide responsible for specific serological activity are not identical with those which determine the inhibitory effect relative to mumps virus. The possible mechanisms of the inhibition of viral multiplication by means of polysaccharides are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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