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. 1949 Jan 31;89(2):233–243. doi: 10.1084/jem.89.2.233

THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS

IV. EFFECT OF SODIUM PERIODATE ON THE ELUTION OF INFLUENZA VIRUS FROM RED CELLS

George K Hirst 1
PMCID: PMC2135856  PMID: 18107973

Abstract

Influenza virus, treated with sodium periodate, was adsorbed well on red cells but lacked the capacity for spontaneous elution. Heated virus was eluted from red cells by the action of cholera vibrio filtrate, unheated influenza virus, and to a small extent by heating at 56°C. Periodate-treated virus was not elutable by these methods but was liberated by exposure of the adsorbing cells to concentrations of sodium chloride of 5 to 10 per cent. This treatment had no effect on elution of heated virus.

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Selected References

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  1. HIRST G. K. The nature of the virus receptors of red cells; evidence on the chemical nature of the virus receptors of red cells and of the existence of a closely analogous substance in normal serum. J Exp Med. 1948 Apr 1;87(4):301–314. doi: 10.1084/jem.87.4.301. [DOI] [PMC free article] [PubMed] [Google Scholar]
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