Abstract
Partially purified suspensions of typhus rickettsiae have been shown to exhibit metabolic activity as evidenced by consumption of oxygen and production of carbon dioxide in the presence of glutamate. Similar activity at a much lower rate occurs in the presence of pyruvate. The rate of oxygen uptake was directly proportional to the concentration of viable rickettsiae, as estimated by their toxicity for mice. Normal yolk sac suspensions prepared in the same manner showed only a very slight oxygen uptake under the same conditions. Glucose was not metabolized by the rickettsial suspensions.
Full Text
The Full Text of this article is available as a PDF (248.9 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cox H. R. CULTIVATION OF RICKETTSIAE OF THE ROCKY MOUNTAIN SPOTTED FEVER, TYPHUS AND Q FEVER GROUPS IN THE EMBRYONIC TISSUES OF DEVELOPING CHICKS. Science. 1941 Oct 31;94(2444):399–403. doi: 10.1126/science.94.2444.399. [DOI] [PubMed] [Google Scholar]
- Racker E., Krimsky I. INHIBITION OF PHOSPHORYLATION OF GLUCOSE IN MOUSE BRAINS BY VIRUSES AND ITS PREVENTION BY PREPARATIONS OF DIPHOSPHOPYRIDINE NUCLEOTIDE. J Exp Med. 1946 Aug 31;84(3):191–203. [PMC free article] [PubMed] [Google Scholar]